Associate Scientist, in vitro Pharmacology and Assay Development

Job description

Position Summary: Metaphore is seeking a highly motivated, detail-oriented, and collaborative Associate Scientist to support in vitro pharmacology and assay development efforts within our Biology team. This role will focus on the design, development, optimization, and execution of cell-based and biochemical assays to support discovery and preclinical programs. The ideal candidate will bring strong hands-on experience in assay development and execution, with the ability to independently troubleshoot and refine assays while contributing to broader program goals. This is a primarily pipeline-facing role with opportunities to contribute to platform development efforts involving complex biological systems. Key Responsibilities: - Design, develop, optimize, and execute in vitro and ex vivo assays to support discovery and preclinical programs, including functional and phenotypic assays. - Perform medium-throughput ligand-binding and cell-based assays (e.g., ELISA, MSD, and reporter or proliferation assays) to characterize biological activity and support hit identification and lead optimization. - Develop and implement assays to evaluate pharmacokinetic (PK) and pharmacodynamic (PD) readou...