Postdoctoral Research Associate - Urologic Surgery

Job description

Position Summary There is an opening for a postdoc in the laboratory of Dr. Kiran Mahajan. The Mahajan lab has been working on studying various signaling mechanism in immune regulation and its role in tumor microenvironment of prostate cancer. The group also studies various epigenetic processes (histone phosphorylation, methylation and acetylation) that drive these diseases and their role in immune modulation. In addition, the lab also has a robust program in development of small molecule inhibitors as therapeutic option for these cancers. The lab has previously identified multiple new signaling events, which play crucial role in various malignancies and cellular homeostasis (Cancer Cell, 2017, Clinical Cancer Research 2022, Journal of Nuclear Medicine 2024). Projects include, but are not limited to, (i) drug development, (ii) the study of cancer immunology using genetically engineered mouse models, (iii) molecular analysis of epigenetic crosstalk, and (iv) the effects of these epigenetic events on the tumor immune response. Investigation of these studies involves the use of state-of-the-art mouse genetics, functional genomics, next-generation sequencing, bioinformatics, molecular...