Postdoctoral Fellow, Quantitative Systems Pharmacology
Pfizer · Cambridge, Massachusetts, US
Role summary Quantitative Systems Pharmacology (QSP) is a scientific discipline that applies mechanistic, mathematical models and disease platforms to improv...
Job description
Role summary Quantitative Systems Pharmacology (QSP) is a scientific discipline that applies mechanistic, mathematical models and disease platforms to improve the robustness and quality of decision-making across the drug discovery and development process, from discovery research to clinical development. The Pharmacometrics and Systems Pharmacology group at Pfizer, together with the Clinical & Translation Biomarkers team, is seeking a highly motivated postdoctoral fellow to develop, advance, and analyze an end-to-end mechanistic QSP model to better understand therapeutic benefits of incretin therapies beyond weight loss and to generate testable hypotheses for novel mechanisms and indications. The successful candidate will hold a Ph.D. in Applied Mathematics, Engineering, Physics, Pharmaceutical Sciences, Pharmacology, or a closely related discipline, with a strong quantitative mechanistic modeling background and a demonstrated record of scientific publication. Postdoctoral Fellowship Overview: The postdoctoral fellow will develop and analyze an end-to-end QSP model that connects incretin pharmacology across tissues to measurable clinical biomarkers and patient-relevant outcomes (e.g...