Senior Scientist, Biophysics

Job description

Senior Scientist Biophysics About the Role: We are seeking an experienced, self-starter, and highly motivated Biophysics Senior Scientists to join our San Diego team to deliver high-quality results and drive small molecule drug discovery. In this role, you will be a key contributor to our small‑molecule discovery engine, designing and executing biophysical strategies that identify high‑quality hits, elucidate mechanisms of action, and accelerate lead optimization. You will work at the center of multidisciplinary project teams, partnering closely with chemistry, biology, and lead discovery to advance programs toward development candidates. The successful candidate will propose, design, and implement new biophysical assays and hit ID approaches (ie. SPR, MST, DSF, NMR), characterize protein-small molecule and protein-protein interactions, and uncover mechanistic insights of our drug discovery targets and lead molecules. You will provide expert interpretation of biophysical results and use data analysis and visualization tools to integrate data with the broader set of data generated at Treeline to drive program decisions. Responsibilities: - Propose, design, develop, and execute bioph...