JobMesh

Senior Expert Science & Technology - Mass Spectrometry - Gene Therapy Analytical Development - Chemistry

Novartis · East Hanover, New Jersey, US

Job Description Summary Location: East Hanover, US #onsite Role Purpose: As a key member of the Analytical Development team, this individual will support dev...

Job description

Job Description Summary Location: East Hanover, US #onsite Role Purpose: As a key member of the Analytical Development team, this individual will support developmental activities to aid in delivering gene therapy to patients. The successful candidate will support technical and development projects designed to characterize gene therapy products with a technical focus on leveraging mass spectrometry. This role will leverage deep Mass Spectrometry expertise to contribute to cross-functional activities including monitoring and characterizing of processes and products as well as to identify opportunities for continuous improvement. Growth mentality and passion to serve patients, technical teams, and development programs is a must. Job Description: Key Responsibilities: - Design, plan, and perform product characterization studies utilizing a deep understanding of protein mass spectrometry. This includes optimizing and implementing experimental and routine analyses using methodologies like; peptide mapping for PTM determination, intact and middle down MS for variant identification, and quantitative methods such as TMT labeling and label-free quantitation - Competitive candidates will also...