Scientist, NMR & Biophysics

Job description

Scientist, NMR & Biophysics About the Role: We are seeking a highly motivated Biophysics Scientist to join our Watertown team to deliver high-quality results and drive small molecule drug discovery. In this role, you will be a key contributor to our small‑molecule discovery engine, designing and executing biophysical strategies that identify high‑quality hits, elucidate mechanisms of action, and accelerate lead optimization. You will work at the center of multidisciplinary project teams, partnering closely with chemistry, biology, and lead discovery to advance programs toward development candidates. The successful candidate will design and implement new biophysical assays and hit ID approaches with a focus on ligand observed and protein observed NMR, along with other techniques such as SPR and DSF. You will provide expert interpretation of biophysical results and use data analysis and visualization tools to integrate data with the broader set of data generated at Treeline to drive program decisions. Responsibilities: - Design, develop, and execute biophysical assays to support hit identification, hit-to-lead, and lead optimization activities. - Establish robust NMR assays to monito...