Director, Neuroscience (In Vitro Cellular Biology)

Job description

Your work will change lives. Including your own. The Impact You’ll Make: Recursion is seeking a Director of Neuroscience to lead the development and application of human iPSC-derived cellular models for neurodegenerative disease drug discovery. This role combines scientific leadership with hands-on execution to advance programs from target identification through lead optimization. You will partner cross-functionally and with external collaborators to deliver high-quality, data-driven insights that accelerate therapeutic discovery. In this role, you will: - Lead design and development of human iPSC-derived cellular models and mechanistic assays for neurodegenerative diseases (e.g., Alzheimer’s, Parkinson’s, ALS) - Drive neuroscience programs from early discovery through lead optimization, establishing robust in vitro assay cascades to enable SAR and decision-making - Design and oversee cellular and molecular assays using high-content imaging and quantitative approaches to interrogate disease biology and mechanism of action - Collaborate closely with chemistry, pharmacology, data science, screening, toxicology, and DMPK teams to advance targets and molecules - Contribute to target va...