(Senior) Machine Learning Engineer
Flagship Pioneering, Inc. · Boston, Massachusetts, US
ABOUT PROFOUND THERAPUETICS ProFound Therapeutics is pioneering the discovery of the expanded human proteome to unlock a new universe of potential therapeutics.
Job description
ABOUT PROFOUND THERAPUETICS: ProFound Therapeutics is pioneering the discovery of the expanded human proteome to unlock a new universe of potential therapeutics. By integrating multi-omics, advanced computation, and translational biology, we aim to reveal and characterize thousands of previously uncharted proteins and systematically explore their role in health and disease. THE ROLE: We are seeking a highly motivated (Senior) Machine Learning Engineer / Data Scientist to join our AI/ML team. This individual will play a central role in designing and implementing advanced machine learning systems that integrate multi-omics, perturbation, and biological knowledge graph data. Working closely with the Head of AI/ML and cross-functional partners, you will develop generative, transformer-based, and causal models — including large language models (LLMs) — within a multi-agent causal AI framework to uncover disease-driving proteins and pathways. The insights generated will directly support therapeutic discovery and development. KEY RESPONSIBILITIES: - Architect and implement scalable ML systems that integrate multi-modal data (genomics, transcriptomics, proteomics, imaging, perturbation dat...