Postdoctoral Research Associate - Pharmacy and Pharmaceutical Sciences

Job description

A postdoctoral position is available in the laboratory of Samuel W. Brady. The lab focuses on identifying and therapeutically targeting key dependencies in pediatric solid tumors (Banu et al., Science Advances 12:eaeb3503 (2026) http://www.science.org/doi/10.1126/sciadv.aeb3503 and cancer genomics, including mutational signatures (Brady et al., Cancer Discovery 2026 http://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-25-0231/783733/Therapy-related-mutational-signatures-in . This position involves the experimental study of key pediatric cancer dependencies, and the identification of new approaches to target them therapeutically. This includes studies of protein signaling, subcellular relocalization, pharmacological studies using existing small molecule inhibitors, and the study of newly-developed compounds and approaches to inhibit essential childhood cancer dependencies. With a general background in cancer biology, pharmacology, and/or chemical biology, the ideal candidate would be familiar with cancer models, protein analysis (such as Western blot and immunoprecipitation), microscopy, cell culture, and molecular biology techniques. This position may also invol...