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Postdoctoral Associate - AI for Brain Tumors

Baylor College of Medicine · Houston, Texas, US

Summary The Postdoctoral Associate will develop next-generation AI models for large-scale perturbation modeling in brain tumors.

Job description

Summary The Postdoctoral Associate will develop next-generation AI models for large-scale perturbation modeling in brain tumors. The project will involve building and applying state-of-the-art machine learning approaches, including foundation models, variational autoencoders (VAEs), and transformer-based architectures, to integrate single-cell and multi-omic datasets. The goal is to decode tumor cellular heterogeneity and tumor microenvironment interactions, and to identify targetable genes, pathways, and therapeutic strategies at single-cell resolution. Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates. Job Duties: - Develops and implements AI models for perturbation prediction: - Designs, trains, and evaluates machine learning models (e.g., transformer-based architectures, VAEs, and foundation models) to predict cellular responses to genetic and pharmacologic perturbations. This includes preprocessing large-scale single-cell and multi-omic datasets, defining model architectures, optimizing training pipelines on GPU clusters, and benchmarking against existing methods. - Integrate and analyze large-scale single...