Scientist III, Bioconjugation (ADC) Process Development

Job description

SUMMARY/JOB PURPOSE (Basic purpose of the job): The Scientist III, Bioconjugation (ADC) Process Development, will have an opportunity to contribute to Exelixis’ Antibody Drug Conjugates (ADCs) technology platforms. The successful candidate will be responsible for the development of scale-able and robust downstream ADC processes and support technology transfer efforts, leading to clinical GMP manufacturing of ADCs. ESSENTIAL DUTIES/RESPONSIBILITIES: - Technical knowledge at design, execution and data interpretation of experiments related to development, optimization, and scale-up of biologics with a focus on ADC Bioconjugation and Purification processes. - Develop Subject Matter Expertise in bioconjugation (ADC) process development and manufacturing in support of CMC activities. - Work closely with research function to understand relevant conjugation chemistries and transition bioconjugation process from research to CMC development. - The ability to identify, evaluate, and implement new and existing technologies to improve process efficiency, control, and understanding. - Experience in applying DOE and other advanced statistical techniques to design experiments (DoE) related to proc...