Postdoctoral Scientist - Alvarez Lab
Howard Hughes Medical Institute · Philadelphia, Pennsylvania, US
Primary Work Address: Clinical Res. Bldg. , Room 405, Philadelphia, PA, 19104-6148 Current HHMI Employees, click here to apply via your Workday account.
Job description
Primary Work Address: Clinical Res. Bldg., Room 405, Philadelphia, PA, 19104-6148 Current HHMI Employees, click here to apply via your Workday account. About the Lab: Freeman Hrabowski Scholar Dr. Juan Alvarez is recruiting creative, collaborative, and highly independent Postdoctoral Scientists to lead new research projects in his lab at the University of Pennsylvania. Learn more about the lab at www.j-radlab.com and about the HHMI Freeman Hrabowski Scholars Program here Our lab studies how differentiated cells become functionally specialized, or “mature” (Alvarez-Dominguez and Melton, Cell 2022). We are particularly interested in how circadian and metabolic rhythms impact pancreatic islet cell maturation (Alvarez-Dominguez et al., Cell Stem Cell 2020), with the goal of building mature human stem cell–derived organoids as models of islet development, physiology, and diabetes cell therapy. Projects will be tailored to the interests of the successful candidate within the following research themes: Modeling human pancreatic islet development and physiological maturation Engineering islet organoids for diabetes modeling and screening applications Circadian clock ontogeny and metabolic...