JobMesh

Senior Scientist, Drug Product Development

Alumis · South San Francisco, California, US

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of...

Job description

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. We are seeking an experienced and highly motivated Senior Scientist for the Drug Product Development group who can work in a collaborative and dynamic environment. The scientist in this role is responsible for activities critical to the development of Alumis’ molecules including generation of pre-formulation packages, formulation selection, and manufacturing process development. This primary focus of this role will currently be on solid oral dosage form development but may involve the development of other dosage forms in the future. Responsibilities: - Hands-on pre-clinical formulation development includes identifying vehicles, excipients, and/or new technologies for poorly water-soluble compounds in support of preclinical PKPD, efficacy, and tox studies. - Execute and/or oversee pre-formulation activities including characterization of physicochemical and solid-state properti...