JobMesh

Senior Bioinformatics Analyst

Cincinnati Children's · US

At Cincinnati Children’s Hospital Medical Center - consistently recognized as one of the nation’s top places to work and a global leader in pediatric researc...

Job description

At Cincinnati Children’s Hospital Medical Center - consistently recognized as one of the nation’s top places to work and a global leader in pediatric research and care - we are driven by a shared commitment to discovery, collaboration, and impact. We are seeking a highly motivated Bioinformatics Analyst or a Postdoctoral Research Fellow at various career stages. Exact position and title will be commensurate with the candidate’s qualifications and experience. The Computational Regulatory Genomics Laboratory develops statistical and machine learning–based methods to understand the fundamental mechanisms of gene transcriptional regulations in various biological contexts. Our research focuses on enhancer regulation and systems-level understanding of enhancer architectures and functions across diverse biological contexts. We integrate multi-omics data, including ChIP-seq, ChIP-exo, CUT&RUN, GRO-seq, csRNA-seq, RNA-seq, ATAC-seq, Hi-C, and single-cell technologies, to delineate heterogeneous architectures of transcription factor binding events and chromatin landscapes at high resolution. The lab broadly collaborates with multiple experimental laboratories, encompassing metabolism, cancer...