Senior Director/Executive Director, DMPK

Job description

JOB SUMMARY: Iambic Therapeutics is seeking an experienced DMPK leader to lead our Drug Metabolism & Pharmacokinetics function. Reporting to senior leadership, you will define the scientific strategy for DMPK from early discovery through IND-enabling studies. You will collaborate with internal and external partners to plan and execute DMPK studies. This is a high-impact, hands-on leadership role for someone who thrives at the intersection of rigorous science and strategic drug development. KEY RESPONSIBILITIES: Lead and manage all DMPK strategy and execution across Iambic's discovery programs, setting clear goals and ensuring alignment with cross-functional program teams. Design and oversee non-clinical ADME/PK studies and PK/PD modeling to enable candidate selection and accelerate IND filings. Serve as the internal DMPK subject matter expert, partnering with medicinal chemistry, biology, toxicology, and clinical teams to interpret data and guide program decisions. Build and manage a high-performing network of CRO partners and academic collaborators to supplement internal capabilities. Lead preparation and review of DMPK sections for regulatory submissions including INDs and NDAs;...