Senior Scientist - Bioinformatics

Job description

The Molecular Profiling and Data Science Department is looking for an enthusiastic and motivated Computational Scientist who values independent research in an open and collaborative working environment. You will participate in original studies that span from basic research to translational studies, directly impacting the lives of patients. You will join a diverse and inspiring team which leverages bioinformatic strategies to optimize key aspects of gene therapeutic products, including expression, stability, splicing, and translation. You will work closely with the Regeneron Genetic Medicines Technology Center (RGM) to advance therapeutic development through cutting-edge computational support. You will utilize genomic and transcriptomic profiling sequencing tools to engineer delivery vehicles, evaluate therapeutic cargo efficacy, and identify the off-target effects of the delivered payload. In this role, a typical day might include the following: Lead computational on-target and off-target characterization of gene therapy programs, utilizing both empirical NGS datasets and in silico prediction models. Build and refine models to predict, score, and prioritize therapeutic off-target e...