Postdoctoral Fellow-MSH-12906-059

Job description

A postdoctoral position in HIV and substance abuse pathogenesis The Volsky lab in the Department of Medicine/Infectious Diseases at Icahn School of Medicine at Mount Sinai, New York, seeks a Bioinformatics Specialist with experience in rodent studies to participate in studies on the interactions between HIV and drugs of abuse in promoting HIV neuropathogenesis and virus- and drug-related behaviors. The studies will be conducted in mice using a model of HIV neurocognitive disease by EcoHIV infection. The research will focus in part on the role of microglia in HIV neuropathogenesis and/or drug abuse. Work will include analyses of single-cell, single-nucleus, or spatial RNA-seq databases from mouse brain to identify key gene determinants of HIV-substance abuse interaction. Functional validation studies in animals or other suitable experimental models are also envisaged, with an objective of future development of therapeutic interventions. Additional preferred skills/experience: -Experience in experimental pathogenesis in animal models -Experience with NGS data generation/analysis -Interest in substance use disorder (SUD) research -2-3 years of experience working with rodents -Track re...