JobMesh

Senior/ Computational Biologist/ ML Scientist

Kernal Bio · Boston, Massachusetts, US

September 24, 2025 Position: Senior Computational Biologist/ ML Scientist Company Overview: At Kernal Bio, we engineer human cells inside the body using sele...

Job description

September 24, 2025 Position: Senior Computational Biologist/ ML Scientist Company Overview: At Kernal Bio, we engineer human cells inside the body using selective mRNA-LNP technology to treat cancer and autoimmune diseases. Our AI-designed mRNAs, delivered via antibody-decorated lipid nanoparticles (LNPs), ensure precise targeting and minimize off-target effects. Our KR-402 program focuses on hematological malignancies and autoimmune disorders, achieving >90% in vivo delivery efficiency with T-cell-targeted LNPs. The KR-335 program, targeting solid tumors resistant to standard immunotherapies, shows a 100x therapeutic index with strong efficacy and tolerability in preclinical models, including mice and non-human primates. With roots at MIT, Harvard, Merck, and BMS, our management team has spearheaded the development of three FDA-approved therapies and holds over 120 patents. Based in Cambridge, MA, and backed by Hummingbird Ventures, Amgen Ventures, NVIDIA, and NASA, Kernal Bio is revolutionizing mRNA therapeutics by leveraging AI to deliver precision treatments within the body. Job Summary: Senior Computational Biologist/ ML Scientist We are seeking a Senior Computational Biologis...