UNIV - Postdoctoral Fellow - Department of Biochemistry

Job description

Job Description Summary The Department of Biochemistry & Molecular Biology at the Medical University of South Carolina (MUSC) invites applications for a Postdoctoral Fellow position in the laboratory of Dr. Huimin Zhang, who joined MUSC in November 2025. The Zhang Lab focuses on DNA damage repair and cancer biology, investigating the molecular mechanisms underlying genomic instability and developing strategies to exploit these mechanisms for cancer therapy. Research emphasizes tumor suppressor genes, oncogenes, and other genes involved in DNA damage response pathways that contribute to tumor initiation, progression, and metastasis. The lab particularly studies how cells respond to chemotherapy and maintain genomic stability, with a focus on topoisomerase-targeting agents (Molecular & Cellular Proteomics, 2025, DOI: 10.1016/j.mcpro.2025.101082; Science Advances, 2023, DOI: 10.1126/sciadv.adi6681; Nature Communications, 2022, DOI: 10.1038/s41467-022-31801-7; Nucleic Acids Research, 2019, DOI: 10.1093/nar/gkz769; Journal of Biological Chemistry, 2016, DOI: 10.1074/jbc.M116.755991). The lab employs a broad range of biochemical, molecular, and cellular approaches, including large-scale...