JobMesh

Specialist - Research-Fixed Term

Michigan State University · Grand Rapids, Michigan, US

Position Summary The Campbell lab studies the molecular mechanisms of autism spectrum disorder (ASD). The lab takes three distinct approaches, all of which u...

Job description

Position Summary The Campbell lab studies the molecular mechanisms of autism spectrum disorder (ASD). The lab takes three distinct approaches, all of which use human cerebral organoids as a human model of early brain development. The first approach is to understand how genes with high confidence ASD mutations alter neurodevelopment. The second approach is to determine how common genetic variants with genome-wide significant association with ASD alter neurodevelopment. The third approach is to expose human cerebral organoids – with a variety of genetic backgrounds – to environmental factors that are associated with ASD risk. Collectively, these approaches will identify genetic and biochemical networks that can be targeted for therapeutics. The funded project involves growth of human cerebral organoids, Nanopore direct RNA sequencing, and single cell RNA sequencing. The successful candidate will take a lead role in research projects, working independently to harvest human cerebral organoids for transcriptomic analyses. Equal Employment Opportunity Statement: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orienta...