Senior/Principal Scientist, CMC Process Development and Manufacturing

Job description

Job Summary City Therapeutics is looking for a passionate Senior/Principal Scientist CMC Process Development and Manufacturing who will be responsible for leading drug substance process development projects for our programs at different stages, with a focus on process development and process characterization for oligonucleotides with novel chemical modifications. The role involves overseeing development projects, supporting non-GMP and GMP drug substance manufacturing, and collaborating with various cross-functional teams both internal and external. The ideal candidate must have strong problem-solving skills, extensive knowledge of oligonucleotide chemistry, and proven experience in oligonucleotide process development. This position is fully onsite and will be primarily located at our Cambridge, MA location. Qualifications: - Lead process development projects including oligonucleotide synthesis activities, process development, optimization and scale-up, and process characterizations. - Collaborate with Drug Substance, Drug Product and Quality Assurance to ensure strong cross functional collaborations and serve the PD/Mfg functional line to ensure that the team meets technical proje...