JobMesh

Senior Principal Scientist - Bioanalytical Sciences

Regeneron · Tarrytown, New York, US

Regeneron's Assay Development Group (ADG) in Bioanalytical Sciences, located in Tarrytown, NY, is seeking a Senior Principal Scientist.

Job description

Regeneron's Assay Development Group (ADG) in Bioanalytical Sciences, located in Tarrytown, NY, is seeking a Senior Principal Scientist. In this exciting role, you will create and execute novel assay strategies for all biotherapeutic modalities, designing experiments, troubleshooting problems, organizing and interpreting experimental results and performing follow-up experiments. A Typical Day in the Role Might Look Like: Develop bioanalytical assay approaches for pharmacokinetic, biomarker assays and immunogenicity assays for a diverse pipeline of novel biotherapeutics, including monoclonal antibodies, bispecifics, antibody-drug conjugates (ADC), adeno-associated virus (AAV), CAR-T, RNA as well as drug target biomarkers to support non-clinical and clinical studies. Supervise a team of scientists in the development and validation of immunoassays for the measurement of drug, drug complexes and anti‑drug antibodies to support new programs. Guides the designs and execution of immunoassays (PK, PD and ADA) by direct reports, based on protocols provided by literature, seminars and other scientists. Suggests troubleshooting experiments for assay-related problems follow-up experiments to fu...