JobMesh

Sr. Scientist, Diagnostic Assay Development

10x Genomics · Pleasanton, California, US

10x Genomics is establishing a diagnostics effort to translate our leading single-cell and spatial genomics technologies into impactful clinical applications...

Job description

About the Role: 10x Genomics is establishing a diagnostics effort to translate our leading single-cell and spatial genomics technologies into impactful clinical applications. We are seeking a highly skilled and motivated Senior Scientist to join the Diagnostic Assay Development team. This is a hands-on bench scientist role with scientific ownership of assay development and optimization, combined with mentorship and technical leadership of junior staff. The Senior Scientist will directly execute, troubleshoot, and refine 10x Genomics–based assays to support development of robust Laboratory Developed Tests (LDTs). What you Will Be Doing: Assay Development & Execution - Independently execute complex single-cell and spatial genomics workflows, including sample processing, library preparation, and sequencing. - Serve as a hands-on technical expert for 10x Genomics platforms (e.g., Chromium, Xenium), with direct responsibility for assay performance. - Systematically troubleshoot and optimize assay workflows to improve robustness, sensitivity, and reproducibility. - Adapt, refine, and extend published protocols to meet clinical, regulatory, and scalability requirements. - Design and execu...