Senior Director, Head of Biology

Job description

Role Overview Vesalius is seeking a Senior/Executive Director-level Head of Biology to lead biological strategy and target validation across our causality-driven discovery platform. This role is responsible for translating human genetic evidence (including GWAS, rare variants, Mendelian randomization, and functional genomics) into rigorous, disease-relevant biological validation and for shaping preclinical programs across multiple therapeutic areas. The ideal candidate brings deep target validation expertise across therapeutic modalities and disease areas, with particular strength in neurodegeneration (including Parkinson’s disease), genomic perturbation tools, and the ability to contribute meaningfully to cardiovascular and immune-mediated biology. You will build and mentor a high-caliber biology team, establish standards for scientific rigor and decision-quality, and partner closely with data science, chemistry, and platform operations to advance targets toward development readiness. Key Responsibilities: - Own Vesalius’s biological validation strategy from human genetics to disease-relevant cellular phenotypes and translational readouts. - Translate genetic and functional genomi...