JobMesh

Director, Operational Excellence- Cell Therapy Manufacturing

AstraZeneca · Gaithersburg, Maryland, US

, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions a...

Job description

About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across the vein-to-vein value stream. You will operate in a matrix with site-based OE Leads. It sets strategy, governs the improvement portfolio, and delivers measurable outcomes in cost, productivity, service, quality, safety, and compliance. Additionally, it builds sustainable capabilities for scale. You Will: Lead end-to-end value stream mapping. Deploy Hoshin/strategy deployment to translate targets, such as COGM, capacity, and service, into a governed portfolio. This portfolio have clear owners, milestones, risks, and benefits. Additionally, create standardized COGM/productivity dashboards and benefit tracking with Finance. Lead programs (cycle time, labor models, MES/EBR enablement, yield, changeovers/scheduling, deviation reduction, automation/technology insertion). Apply the AZ Lean Model (A3, VSM, standard work, daily/tier management, leader standard work, adapted SMED). Facilitate development of business processes for training, batch execution, deviations, and patient/lot scheduling an...