JobMesh

Scientist I, Immune Evasion

Dyno Therapeutics · Watertown, Massachusetts, US

The Role Scientist I, Immune Evasion. Advancing Dyno’s immune evasion capabilities by developing and executing innovative assay strategies that enable the di...

Job description

The Role Scientist I, Immune Evasion. Advancing Dyno’s immune evasion capabilities by developing and executing innovative assay strategies that enable the discovery and clinical readiness of next-generation capsids. Job Type: Full Time, onsite: Location: Watertown, MA: How You Will Contribute: As a Scientist I, you will independently lead and evolve Dyno’s high-throughput immune evasion assay platform, driving antibody evasion studies that support CNS and Muscle capsid discovery programs and partnering cross-functionally to shape experimental strategy and address technical gaps. You will also help expand the team’s immune evasion capabilities beyond pre-existing antibodies to emerging clinical readiness challenges, including re-dosing, T-cell responses, complement activation, and innate immunity. At Dyno, every role is mission-driven. Whether in science, engineering, operations, or business, each AAViator contributes to solving some of the most complex challenges in genetic medicine. Responsibilities: - Independently execute and support high-throughput immune evasion (IE) assays, including antibody neutralization and total antibody immunoprecipitation (tAb IP) workflows, to ensure...