Research Assistant - Neuroscience and Pharmacology (Tomchik Lab) - Stem Cell Research

Job description

Research Assistant - Neuroscience and Pharmacology (Tomchik Lab) - Stem Cell Research - ( 26003181 ) Description The Carver College of Medicine Department of Neuroscience and Pharmacology (Dr. Tomchik lab) is seeking a Research Assistant. This Research Assistant will carry out research on the mechanisms of mechanisms of metabolic alterations in neurofibromatosis type 1, using both human induced pluripotent stem cells and Drosophila melanogaster. Our research focuses broadly on neuronal plasticity and metabolic alterations in genetic disorders such as neurofibromatosis type 1 (NF1). This disease affects 1 in ~3000 individuals, causing a range of symptoms, including tumor formation, increased incidence of neurocognitive symptoms, and metabolic alterations. This project is focused on the mechanisms of the metabolic alterations. We have recently discovered that loss of neurofibromin (the protein mutated in NF1) alters metabolic rate via neuronal effects (Botero et al., 2021; Nature Communications 12(1):4285) and are diving deeper into the underlying mechanisms. This position provides an opportunity to carry out research relevant to human disease at the intersection of neuroscience and...