Postdoctoral Scholar

Job description

Department Overview This position is focused on research-based computational and data-driven analysis of CRISPR screening datasets to study metabolic changes in cancer and other disease systems. Responsibilities include, but are not limited to, processing and analyzing large-scale CRISPR perturbation data, integrating CRISPR screening results with multi-omics datasets, developing computational pipelines to identify metabolic vulnerabilities and regulatory mechanisms, and supporting study coordination, data management, and related regulatory documentation. Function/Duties of Position: - Processing and analyzing CRISPR screening data, including data curation, normalization, quality control, hit identification, and downstream statistical analysis using Python, R, and other relevant software tools. - Integrating CRISPR perturbation data with transcriptomics, metabolomics, proteomics, and other omics datasets to identify metabolic pathway alterations, gene dependencies, and functional mechanisms. - Assisting in the development and implementation of robust computational pipelines, algorithms, and reproducible workflows for analyzing CRISPR-based functional genomics data and metabolic phe...