Scientist, In Vitro Biology

Job description

The Role: ModernaTX, Inc. seeks a Scientist, In Vitro Biology for its Cambridge, Massachusetts location. Here’s What You’ll Do: Manage technical oversight and troubleshooting of various types of laboratory equipment, particularly for high-content confocal microscopy. Propose, establish and implement a wide range of optical microscopy and imaging techniques to investigate the in vitro pharmacology of nucleic acid and LNP delivery systems. Investigate a variety of molecular biology and cell engineering methods to generate relevant in vitro model systems to interrogate nucleic acid and LNP delivery systems. Manage and oversee the technical work of co-ops or junior staff by providing scientific guidance and training. Develop quantitative methods to measure specific biomolecules of interest within cultured and primary cells, and tissues, as well as methods to study mRNA endosomal escape, and mRNA and protein subcellular localization, mRNA half-life, and protein translation. Independently conceptualize, generate and assemble in vitro cell-based data packages to support the advancement of Moderna’s nucleic acid and LNP delivery platforms and therapeutic pipeline. Identify, introduce, and...