Senior Project Manager – PMO (GMP & non-GMP)

Job description

Summary of Role: The Senior Project Manager – PMO is responsible for end-to-end delivery of sophisticated capital and infrastructure projects across AstraZeneca’s U.S. R&D network, including GMP and non-GMP facilities. This role leads projects from early concept through closeout, partnering with Site Leadership and Global stakeholders to define scope, evaluate infrastructure capacity and impacts, assess risk, and build capital strategy early in the lifecycle. The Senior Project Manager ensures initiatives are aligned with site strategy and executable within active, regulated environments. The role provides full project lifecycle accountability, scope, budget, schedule, risk, governance, and partner alignment, ensuring delivery of safe, compliant, and operationally sustainable facilities. The Senior Project Manager leads cross-functional teams including Senior Project Engineers, external design firms, contractors, Quality, SHE, and Facilities to ensure projects are implemented with operational excellence and regulatory integrity. Responsibilities: Project Leadership & Accountability Lead front end planning: scope definition, feasibility, infrastructure capacity assessments, and cost...