Senior Scientist, Translational PKPD
AstraZeneca · Cambridge, England, GB
Job Title: Senior Scientist, Translational PKPD Location: Cambridge UK Do you have expertise in Oncology, and a passion for PKPD modeling and DMPK science, a...
Job description
Job Title: Senior Scientist, Translational PKPD Location: Cambridge UK: Do you have expertise in Oncology, and a passion for PKPD modeling and DMPK science, applied to Cancer biology? Would you like to apply your expertise to impact the lives of patients in a company that follows the science and turns ideas into life changing medicines? As a Senior Scientist/Associate Director in Translational PKPD, you will have the opportunity to drive strategy and provide global leadership in DMPK science on Antibody Drug Conjugates (ADCs), Radioconjugates (RCs) large molecules. Your role will involve providing projects with DMPK support, exploring the PK/PD/Efficacy relationships in pre-clinical models, using these models to build a quantitative understanding of the dose & schedule requirements for therapeutic intervention across different patient populations as a single agent and combined with other agents. Essential for the role: Representing the Translational PKPD group and providing overall scientific leadership for cross functional and external collaborations involving DMPK. Exploring the effects on target and pathway to understand the requirements for efficacy and set a candidate drug tar...