Post Doc - Open Rank - Ruscetti Lab

Job description

Additional Information Mechanisms and models of immune suppression and metastasis in cancer A postdoctoral research position supported by long-term federal funding is available in the laboratory of Marcus Ruscetti, Ph.D. to work on projects to: (1) Develop innovative mouse models of prostate cancer to determine genetic determinants of immune suppression and metastasis. (2) Uncover heterogeneous senescent cell types and niches that promote tumor progression using single cell and spatial approaches. These projects, and my laboratory, lie at the intersection of cancer genetics and tumor immunology, and at the interface of basic science and translational medicine. Our long-term goals will be to translate our basic understanding of how genetic alterations and senescence biology regulate critical tumor-immune interactions into the development of small molecules and other therapeutic strategies to treat patients with deadly pancreatic and prostate cancers. Our lab is part of the Department of Molecular, Cell and Cancer Biology (MCCB) at the University of Massachusetts Chan Medical School (UMCMS) in Worcester, MA, giving us access to a multitude of state-of-the-art core facilities, shared...