JobMesh

Scientist II / Senior Scientist, I, tLNP Process Development

AbbVie · North Chicago, Illinois, US

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and ad...

Job description

Company Description About AbbVie: AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube. Description: The target lipid nanoparticle (tLNP) process development team is seeking a highly motivated, talented, and innovative scientist to develop manufacturing processes for tLNP from purified mRNA into purified tLNP bulk drug product. The successful candidate will help advance understanding unit operations such as mRNA encapsulation, bioconjugation, and tangential flow filtration, as well as scaling up lab processes into pre-clinical, clinical, and commercial scale manufacturing processes. Targeted lipid nanoparticles (tLNPs) represent a key new modality to enable the effective delivery of mRNA. The tLNP chemistry, manufacturing, and control...