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Bioinformatics Research Scientist (TIRTL Collaborative Center)

St. Jude Children's Research Hospital · Memphis, Tennessee, US

See Job Posting Description Position Overview The Tracking the Immune Repertoire of Tumor Lymphocytes (TIRTL) Bluesky program in the Host–Microbe Interaction...

Job description

See Job Posting Description Position Overview: The Tracking the Immune Repertoire of Tumor Lymphocytes (TIRTL) Bluesky program in the Host–Microbe Interactions Department at St. Jude supports multiple institutional research and clinical programs focused on immune repertoire profiling. Building on the foundational TIRTL‑seq (Pogorelyy and Kirk et al., Nature Methods 2025) method, we provide cohort scale T cell and B cell receptor (TCR and BCR) sequencing, enabling research in cancer immunology, infectious disease, and antibody discovery across the institution. We are seeking a Bioinformatics Research Scientist to play a key role in developing, maintaining, and scaling robust computational pipelines that support high-throughput immune repertoire sequencing and antibody discovery across cancer and infectious disease programs. This individual will work closely with experimental scientists, clinicians, and data science teams to deliver reproducible, production-ready analyses as part of a centralized service. Job Responsibilities: - Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and ove...