Analytical Development Research Scientist, Cell and Gene Therapy Proteomics

Job description

Job Description General Summary: Vertex Pharmaceuticals is seeking a research scientist to join the analytical development, cell and gene therapy team. This scientist is expected to serve as a key contributor in expanding our proteomics mass spectrometry characterization capabilities for supporting cell and gene therapy program development. The primary focus of this role will be on proteomics analysis for stem cell differentiation and leveraging multi-omics tools to achieve deeper understanding of cell therapy products. Extensive hands-on experience in liquid chromatography-mass spectrometry-based proteomics is required. The individual in this role will collaborate closely with research, process development, manufacturing, regulatory, and quality to develop and innovate Vertex's next generation cell and gene therapy products. Key Duties and Responsibilities: Provide hands-on support for mass spectrometry-based proteomics characterization and perform biological pathway & bioinformatics analysis. Mass Spectrometry analysis includes but not limited to tandem-mass-tag (TMT) and label-free quantification, data-dependent and independent acquisitions, sub-cellular fractionations, Post tra...