Principal Epidemiologist, FSP

Job description

The Principal Epidemiologist will Leads high-complexity epidemiology, pharmacoepidemiology and RWE workstreams from question framing through protocol/SAP development, collaborating with analysts/programmers/vendors, and delivery of scientifically defensible, client-ready outputs. Serves as a scientific escalation point, maintains clear status/risk visibility, and mentors staff while applying good practice and regulatory expectations for observational evidence. Responsibilities: - Lead development of key scientific deliverables, including study concepts, protocols, and SAPs, ensuring scientific rigor and operational feasibility. - Respond to rapid epidemiological requests, including safety questions and information requests; frame uncertainty and limitations clearly for decision-makers. - Evaluate and recommend fit-for-purpose real-world datasets (e.g., EHR and medical claims), including relevance, completeness, traceability, and key bias risks. - When applicable, assess or support use of registries for evidence generation and advise on strengths/limitations for the research question. - Apply good pharmacoepidemiology practice across planning, conduct, interpretation, and communicat...