Research Assistant III- Transgenic Mouse Models

Job description

Status Full-Time Standard Hours per Week: 40 Job Posting Category: Research: Job Posting Description: Position Summary: The Alt Lab is seeking a highly motivated and detail-oriented individual for a Research Assistant III role. Our Alt lab investigates the molecular mechanisms underlying V(D)J recombination, class switch recombination, and somatic hypermutation in developing and activated B lymphocytes. We apply these insights to generate mouse models that support HIV-1 research, vaccine development, and antibody-based therapies. This role combines hands-on experimental work with technical expertise, regulatory compliance, and leadership responsibilities, including management of lab operations, mentoring junior staff, and maintaining adherence to institutional protocols. Key Responsibilities: - Perform advanced embryo manipulation techniques, including microinjection of pre-implantation embryos with mouse stem cells and aseptic surgical transfer to the uterus or oviduct. - Generation and maintenance of transgenic and knockout mouse models in a barrier-level facility. - Maintenance of mouse colonies, including specialized care for immunodeficient models. - Troubleshoots procedures i...