Scientist/Senior Scientist, PK/PD Assays

Job description

About NewLimit NewLimit is seeking a Scientist or Senior Scientist with deep expertise in molecular biology, pharmacokinetics and translational biomarker assay development. In this role, you will lead the design, development, and qualification of pharmacokinetic (PK) and pharmacodynamic (PD) assays that characterize the biodistribution and biological activity of our mRNA-LNP medicines in preclinical and IND enabling studies. You will serve as a technical leader within our bioanalytical function, shaping biomarker assay strategy and partnering cross-functionally to advance our therapeutic programs toward IND-enabling milestones. What you’ll do: - Own the end-to-end design, development, and qualification of PK and PD biomarker assays across various platforms to support preclinical and IND-enabling studies - Discover and validate pharmacodynamic biomarkers to support the clinical development of drugs across multiple programs - Drive data analysis, interpretation, and reporting for bioanalytical studies to support program decision-making with audit-ready data packages - Contribute to sample processing workflows including tissue harvesting, primary cell culture, and complex matrix handl...